Tomoyuki Ito

Latest

• Discovery and affinity maturation of antibody fragments from an unfavorably enriched phage display selection by deep sequencing and machine learning
• Extensive antibody search with whole spectrum black-box optimization
• Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning
• Machine-Learning-Guided Library Design Cycle for Directed Evolution of Enzymes: The Effects of Training Data Composition on Sequence Space Exploration